Tackling the Glycan Isomer Challenge for your Biotherapeutics

About This Webinar

Sifting through Glycans? Child’s Play with Byos and MOBIE.

N-linked glycosylation is a critical attribute which impacts pharmacological function, safety and efficacy. As minor changes to production processes can influence both glycan structure and composition, glycans must be monitored. However, characterization of N-linked glycosylation is analytically challenging due to innate glycan microheterogeneity.

During this webinar we discuss the use of the MOBIE® High-Resolution Ion Mobility Mass Spec Platform to improve analysis of released N-linked glycans. Focus will be on the applicability for profiling complex glycan isomeric mixtures and the straightforward analysis of this 4D Ion Mobility data using HRIM-Byos modules from Protein Metrics

This session was recorded in December 2022

Key Learning Objectives

  • Current challenges in N-linked glycan characterization
  • The applications of SLIM-based separation with MOBIE
  • Strategies for improving protein therapeutic characterization with MOBIE
  • Learn how powerful software can help you get the get the glycan assignment right