Byonic Protein Identification

Byonic is a full tandem mass spectrometry (MS/MS) search engine for comprehensive peptide and protein identification

Leading Peptide and Protein Identification Software

Byonic provides unequaled sensitivity and high throughput workflows for quick, accurate mass spectrometry analysis

User Friendly, Vendor Neutral Protein Identification Software

Designed for ease of use, Byonic seamlessly handles diverse proteomics experiments, including data-dependent, data-independent, bottom-up, top-down, glycoprotein, and phosphoprotein analysis.

Byonic's broad compatibility with mass spectrometry data formats (CID, TOF-TOF, QTOF HCD, ETD/ECD, EThcD) ensures flexibility across different instrument platforms.

Accurate Scoring and Wide Searches

Byonic improves usability and greatly decreases the rate of inadvertent mistakes by setting database search parameters in a semi-automated, guided fashion.

Byonic is more sensitive (more true positives), specific (fewer false positives), and enables a wider variety of searches than other search engines.

High Throughput Workflows & Reporting

Byonic optimizes search engine performance for high throughput workflows with focused databases, lists of prebuilt modifications, searchable common contaminants, and multi core architecture.

Byonic provides useful output reports of identified glycopeptides/proteins.

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Full Tandem Mass Spectrometry Search Engine

Customizable search options enable Byonic to focus its effort on the candidate peptides most likely to match mass spectra, finding more true matches more quickly than any other proteomics search engine.

Modification Fine Control

Byonic is optimized for the complex modification search of peptides, which can be used to search for various combinations of modification types.

Detailed control of the types and numbers of post-translational modifications allowed on candidate peptides focuses search efforts on peptides most likely to match mass spectra.