Byos Protein Characterization Software
Byos desktop software offers comprehensive mass spectrometry analysis workflows providing robust biotherapeutic protein characterization and reporting
All Byos Workflows
Intact, Sub-unit, and Native Analysis
- Ligand binding
- Protein-protein interaction
- Protein and subunit ID
- Glyco-profiling
- ADC and DAR analysis
- Charge Variants by iCIEF-MS and CE-MS
Peptide-level Analysis
- Hotspot analysis
- Peptide mapping
- PTM analysis
- HCP analysis
- Sequence variant analysis
- Epitope mapping
Multi-Protein Quantitation
- Label-free, relative quantification of complex proteins
- Proteome profiling and full protein characterization
- Rapid sample prep and MS quality check
Oligos
- Oligonucleotide workflows
- Impurities and clips
- Sequence confirmation for known oligos
De Novo Sequencing
- Hands-free, automated sequencing of purified monoclonal antibodies
Chromatogram
- MAM workflows
- CE-UV data; SEC-UV, LC-UV & other chromatographic workflows
- Import of 2D trace data
Higher Order Structure
- HDX and FPOP workflows
- Epitope mapping, paratope mapping, other higher order structure work
- Representation in .pdb format
Intact Reconstruction
- Correlate deconvoluted intact data with peptide mapping data
- PTM quantification, degradation or conjugation analyses
- Determine if acquisition parameters require optimization
MOBILion HRIM
- Workflows for Mobie
- Released Glycan, Intact and Peptide mapping workflows
icIEF MS
- Intabio iCIEF workflows
- Representation on a pI axis with deconvolution
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Knowledge Base
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