Peptide-Level Analysis

Comprehensive tools for characterizing biotherapeutics such as monoclonal antibodies and vaccines. Gain insights into primary structure, modifications, and impurities to support development and quality control.

The proprietary Byonic search engine accurately identifies peptides using MS/MS data. Its fine-grained modification control tailors searches and minimizes false positives, handling complex data from various fragmentation techniques.

The workflow allows for label-free peptide quantification alongside MS/MS identification. It uses the extracted ion chromatogram area from the MS1 trace, providing a robust and sensitive alternative to isotopic labelling.

Organize and manipulate peptides lacking MS/MS data. Import, match, and merge peptide lists from CSV files, allowing for efficient transfer of annotations and incorporation of previously identified peptides.

Visualize protein sequence coverage, chromatograms, spectra, and isotope plots for enhanced data understanding. The peptide workflow generates customizable reports for a comprehensive overview of analyses.

Characterize and quantify post-translational modifications like oxidation, deamidation, and glycosylation. Tools like automated aspartic acid isomerization and mod validator ensure accurate and reliable PTM analysis.

The peptide workflow is designed for high-throughput analyses, essential for handling large sample sets. Features like batch processing, automated analysis, and streamlined reporting enable efficient processing and interpretation. Integration with Byosphere further enhances data management and collaborative analysis.