Automating QC in Discovery Therapeutics
John Patrick from Janssen discusses how automating high-throughput LC-MS and data processing revolutionizes biotherapeutic discovery‚ rapid QC of diverse molecules boosts efficiency and slashes turnaround times
About This Webinar
Automating QC In Discovery Therapeutics : Leveraging Byosphere to Maximize Potential in High Throughput Intact MS QC
Presented by John Patrick, Senior Scientist, Janssen at North American UGM 2024
This webinar goes through the intricate processes of molecule discovery and the development of biophysical testing methods aimed at understanding the properties of various molecules in the context of disease. The discussion highlights the team’s commitment to not only advancing scientific understanding but also directly impacting patient care by accelerating the process from discovery to application. The focus is on exploring a variety of molecular forms beyond traditional levels, employing advanced techniques to ensure the production of high-quality molecules, and understanding the liabilities associated with these molecules as they progress through the development process.
The latter part of the webinar shifts towards the practical applications of these discoveries in a laboratory setting, emphasizing the use of automated systems to enhance the throughput of protein production and analysis. This includes the integration of high-throughput liquid chromatography-mass spectrometry (LC-MS) workflows and the strategic use of metadata to streamline the analysis process, thereby reducing turnaround times and increasing efficiency. The discussion also covers the challenges of managing and adapting to the fast-paced and ever-changing landscape of molecular discovery, highlighting the importance of flexibility and adaptability in both the technological and procedural aspects of the field.
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