Oligonucleotide IP-RPLC-MS/MS for mRNA Sequence Characterization
Digested oligonucleotide IP-RPLC-MS/MS characterizes mRNA sequence, 5’ cap, and 3’ polyA tail.
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Characterization of mRNA PQAs is necessary to ensure safety and efficacy. LC-MS/MS digested oligonucleotide sequence mapping can characterize the 5’ cap, oligo sequence, and 3’ PolyA tail in a single assay.
