Research Spotlight on Multispecifics
The latest in multispecifics with videos on bispecific antibody stability, mispairing, and effective characterization methods.
Series Content
Bispecific IgG1 Characterization
INSIDE THE VIDEO
Ingrid Grunert from Roche Diagnostics examines bispecific 'knob into hole' IgG stability under stress, identifying key degradation variants and their impact on antibody potency.
LENGTH
6 mins
Characterize Bispecific Antibodies
INSIDE THE VIDEO
Our intact reconstruction workflow rapidly characterizes bispecifics, identifying chain mispairing, glycan profiles, and PTMs to streamline accurate bispecific analysis.
LENGTH
3 mins
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Workflow How-Tos
Knowledge Base how to guides for using a variety of workflows
Byos General
Knowledge Base general articles for using Byos
Application Notes
Application notes on a variety of subjects
Byonic
Knowledge base commonly asked questions about Byonic.
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Byosphere enhances LC-MS analysis with custom searches, dashboards, automated workflows, audit trails, and project management.
PUBLICATIONOptimization of Disulfide Linkages in Bispecific Antibodies
Disulfide linkages in the complex cysteine-engineered stapled scFv for bispecific antibodies are optimized and characterized.
PUBLICATIONLab of the Future: Fully Automated System for High-Throughput Mass Spec Analysis
A state-of-the-art, integrated, multi-instrument automated system for MS characterization of biotherapeutics.
WEBINARIntact Characterization of Multispecifics
Learn about multispecific antibodies and the use of 2D LC-MS for improved production and analysis.