What's New in Byos and Byosphere 4.4

Features available in Byos 4.4

A new feature for retention time calibration using internal reference glycans is now available for more confident released glycan assignments.
Peptide Analysis workflows now include a feature to display glycan cartoons on glycopeptides in reports
Chromatography workflows have been updated to allow manual candidate additions of glycopeptides
Fast XIC options have moved from the advanced parameter section to the processing nodes tab in the graphical interface
Peptide MS2 spectra now have optional annotation of internal fragments in the spectrum viewer
Disulfide processing and annotation in chromatogram workflows are improved in several ways; allowing the import of validated peptide projects, allowing trace labelling of disulfides and new disulfide specific reports
Delta masses in intact can now be assigned to selected samples for simplified Intact MS result generation
There are several key improvements in our Oligonucleotide workflow – MS2 data validation by selecting or restoring best MS2 spectrum annotation; New building blocks added for improved coverage of assembled nucleotides; Sample input tab to import sample information via csv files; new Mass XIC widget; Improved impurity analysis for clipped sequence variants
We have introduced the ability to generate Volcano plots in our reports; this feature is available in all workflows.
Chromatogram comparison projects now enable direct input of MS samples as reference rather than reference projects

Byosphere Virtual Client – Byosphere Byos client is installed on a server VM in the Byosphere data center and accessed by the end user via remote desktop
Users can now view other file types in directly in the Byosphere browser, e.g., pdf, png, jpeg, etc., as well as custom rendering for certain csv files
For improved data processing and job manipulation a new feature enables cancellation of running or queued jobs from the desktop Jobs tab
Advanced option to import metadata information from files or added during project creation
Chromeleon CDS generated data can now be accessed directly from the biosphere client file browser