What's New in Byos and Byosphere 5.4

Byos and Byosphere 5.4 Feature Overview

Version 5.4 brings new features and functionality including a new Intact Reconstruction workflow, a new Charge Variant analysis with reconstruction workflow and a new Digested Oligonucleotides workflow.

Top features available in Byos 5.4

  1. New Intact Reconstruction workflow to correlate peptide level PTM information with intact protein analysis
  2. New Charge Variant analysis with reconstruction workflow to correlate isoelectric point (“pI”) - based analysis results such as iCIEF data with peptide mapping data
  3. New Digested Oligonucleotides workflow now extends oligo analysis of digested samples – DNA and mRNA
  4. New MS1 isotope envelope confidence value for peptide mapping workflows
  5. Enhanced in-source artifact detection to distinguish between sample analysis artifacts from actual sample degradation
  6. XIC enhancements for more consistent AUC calculations and detection of peptide isoforms

Top features available in Byosphere 5.4

  1. Dashboards with reporting across analysis methods: Template for monitoring Glycosylation at peptide and intact levels
  2. New Intact Dashboard Template for monitoring intact proteins
  3. New File Inspection tool for Dashboard visualizations to review contributing data files
  4. Enhanced Job status notification and reports in Byosphere
  5. CSV Export for file search results from Byosphere

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