High throughput screening and data analysis using Native Mass Spectrometry and Byos

About This Webinar

OMass Therapeutics: Making a Herd of Elephants Fly

Native mass spectrometry (MS) has emerged as a powerful analytical technique to study proteins and their non-covalent complexes. This includes interactions with small-molecule drugs. Under carefully optimized instrumental conditions it is feasible to quantify the drug dissociation constant (Kd). Given the speed and the low amount of sample needed, native MS could bring tremendous advantages in understanding protein-drug interactions in a high-throughput manner.

In this webinar, Kleitos Sokratous, will present OMass’ in house high-throughput native MS screening platform combined with high-throughput data processing.

This session was recorded in November 2022

Key Learning Objectives

  • A general overview of Native MS and how it can be used as a tool to probe protein-ligand (drug) interaction and quantify binding affinity
  • Utilizing native MS as a technology for high-throughput screening in drug discovery
  • Processing native MS data using Byos