Research Spotlight on Intact Mass
Watch this video on a novel serum stability assay, enhancing accuracy in biologics screening with in vitro methods.
Novel in vitro Serum Stability Assay
INSIDE THE VIDEO
Yihan Li from Abbvie highlights optimized workflows for screening stable biologics, using NISTmAb or Fc fragments as internal standards to improve data quality in LC-MS analysis
LENGTH
7 mins
Learn More
Intact How-Tos
Knowledge Base commonly asked questions about intact workflows
Workflow Setup for Low MW (<10 kDa) Isotopically Resolved Peptides
Knowledge Base article on setting up a workflow for low MW peptides
Intact Analysis of a Purified Therapeutic Protein Incorporating Top-Down Fragmentation
Application note for Intact analysis
Add an optical trace (UV, FL, etc.) to a project in Intact and Chromatogram workflows
Knowledge Base Article for Intact and Chromatogram workflows
More Resources
VIDEO SERIESWorking with Intact Mass Workflows
Run intact mass workflows in Byos. Manage data, sequences, masses, deconvolution, and generate reports for ADCs, glycosylation, and oligos.
VIDEO SERIESWorking with Reconstruction Workflows
Perform intact reconstruction and charge variant analysis. Set up projects, configure processing nodes, and align CIEF traces effectively.
GUIDEQuick Start Guide to Intact Analysis
An easy guide to getting started with intact, reduced, ADC, intact reconstruction, and IntaBio icIEF-MS workflows.
PUBLICATIONLab of the Future: Fully Automated System for High-Throughput Mass Spec Analysis
A state-of-the-art, integrated, multi-instrument automated system for MS characterization of biotherapeutics.