Request demo
Featured Resources
45:51
Implementing an Enterprise Solution for MAM with LC-UV-MS

Move from the Desktop environment to a true Enterprise one with the same workflows. Byosphere® brings the capability to create dashboards, provide queries, and get away from cutting and pasting from hen external data repositories.
5:34
MS-Based De Novo Sequencing of mAbs Using Multiple Proteases and a Dual Fragmentation Scheme

By using multiple proteases and dual fragmentation the authors are able to get the most accurate sequences and the best depth of coverage whilst optimizing protocols for de novo antibody sequencing

17:24
Database Search of Tandem Mass Spectrometry of Oligonucleotides

In collaboration with the University of Texas at Austin, Rose discusses MS1 and MS2 analysis of oligonucleotides and the application of Byonic proteomics features for these molecules
49:25
Automation of Glycan and Peptide Mapping and Improving Efficiency and Quality

More samples, more tests and more complex modalities. Sound familiar? As Pfizer increased the number of assays to perform, Thomas Powers underscores that it is also critical to automate original routine assays and describes challenges tackled along the path.
56:09
Intact Antibody and Plasma Glycoprotein Analysis with Native MS

Albert Heck talks about how Native MS can provide detailed information about the structural integrity, glycosylation patterns, drug loading and non-covalent interactions of mAbs and other biopharmaceuticals.
24:47
Native MS and Cell Line Development

With increasing complexity and volume of biotherapeutics, Janssen describe how they are implementing Byosphere to bring clarity to manage their workflows and deliver concise information when and where its needed.
33:49
Monitoring System Suitability – Byosphere Dashboards

Comparing batches? Assessing digestion completion? Tracking over-alkylation? Learn about the rational for the types of dashboard constructed to monitor these important aspects of laboratory operations.
5:37
Detailed Analytical Characterization of a Bispecific IgG1 CrossMab Antibody of the Knob-into-Hole Format Applying Various Stress Conditions Revealed Pronounced Stability

A panel of stress conditions ( including temperature, pH, oxidizing agents, and forced glycation) were applied to identify and functionally evaluate critical quality attributes in the complementary-determining and conserved regions of a bispecific antibody was applied in this study.
posters
published articles
Briefs
Insights
Download Information & system requirements
×