Featured Resources
Three Channel Charge Deconvolution

There are two quite different methods for determining the charge of m/z peaks:  peak spacing for isotope-resolved masses, and ratio relations among peaks for isotope-unresolved masses. Most software uses one method or the other, but Protein Metrics Intact Mass can use both information channels simultaneously, as well as a third channel...

Database Search of Tandem Mass Spectrometry of Oligonucleotides

In collaboration with the University of Texas at Austin, Rose discusses MS1 and MS2 analysis of oligonucleotides and the application of Byonic proteomics features for these molecules

Intact Antibody and Plasma Glycoprotein Analysis with Native MS

Albert Heck talks about how Native MS can provide detailed information about the structural integrity, glycosylation patterns, drug loading and non-covalent interactions of mAbs and other biopharmaceuticals.

Analysing the SARS-CoV-2 glycan shield with mass spec

Why are we interested in virus glycosylation in general? Max Crispin from the University of southampton gives us an intrudction to the topic as well as a deep dive into the elucidation of the SARS-CoV-2 Glycan shield

High throughput screening and data analysis using Native Mass Spectrometry and Byos

Under carefully optimized instrumental conditions it is feasible to quantify the drug dissociation constant (Kd). OMass Therapeutics presents in house high-throughput native MS screening platform combined with high-throughput data processing.

Characterizing the glycan shield of the Hepatitis C E1E2 glycoprotein complex using mass spectrometry

Maddy Newby takes us through the steps for unravelling the structural details of the E1E2 glycoprotein complex whilst also uncovering a novel glycan site within a non-canonical N-linked glycan site.

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