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Featured Resources
42:39
Automated de novo mAb Sequencing for a Modern Biotech

Using the right practical tools, de novo sequencing now can be easily turned into an in-house, higher throughput procedure with extremely high confidence.
30:17
Keeping it all together – Bacterial Cell Envelope Structure

Kelsi Sandoz describes work where they have used advances in mass spec methodology to answer a 50 year standing question in basic bacterial structure
43:00
Harnessing Novel MS Approaches (MAM, IEX-MS) to Accelerate Biotherapeutic Development and Analysis

MAM workflows are implemented differently according to the vagaries of your organisation. Ben Niu speaks to the Astra implementation across product and process characterization to optimise throughput whilst respecting robustness and variability .
56:09
Intact Antibody and Plasma Glycoprotein Analysis with Native MS

Albert Heck talks about how Native MS can provide detailed information about the structural integrity, glycosylation patterns, drug loading and non-covalent interactions of mAbs and other biopharmaceuticals.
29:34
Biosimilar Characterization

Seamlessly move between non-GxP and GxP to satisfy regulatory requirements with Byosphere. Regardless of the mass spec platform scientists can create workflows that allow comparisons with speed and with confidence
2:38
Rapid Detection of Cross-Linked Dipeptides

The new Byos workflow resulted in the detection a photo-induced cross-linked dipeptide with unknown linker chemistry, which was subsequently identified as a cross-linked dipeptide with a novel Cysteine-Tryptophan linkage.

38:23
Tackling the Glycan Isomer Challenge for your Biotherapeutics

As minor changes to production processes can influence both glycan structure and composition, glycans must be monitored. However, characterization of N-linked glycosylation is analytically challenging due to innate glycan microheterogeneity.

37:52
EU UGM 2023: Annotation of topdown mass spectra of proteins and oligonucleotides

The latest on our Oligo workflows including long digested oligonucleotides - especially mRNAs
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