Featured Resources
41.26
Unraveling the Twin Tales of Biosimilar and Innovator Glycans

N-glycans are omnipresent in the Fc region of monoclonal antibody products. Modifications to a glycan profile can impact a protein’s stability/folding, binding affinities, effector functions, clearance rates, and/or immunogenicity.

42:39
Automated de novo mAb Sequencing for a Modern Biotech

Using the right practical tools, de novo sequencing now can be easily turned into an in-house, higher throughput procedure with extremely high confidence.

56:32
An Implementation of Vendor-Neutral Multi-Attribute Method (MAM)

Ben Niu speaks to setting up automatable workflows from sample preparation all the way through to data analysis and capable of handling a large number of samples.

38:20
EAD: Making characterization of complex biotherapeutics routine

A new fragmentation technique with Sciex's ZenoTOF 7600 with a deep dive into the characterization of PTMs, S-S bond mapping and more with Byos

33:28
質量分析によるオリゴヌクレオチド分析:配列の表示および自動化はもはやシーシュポスの作業(果てしない徒労)ではない

For fast ranking during expression vector design and clone selection, Lonza's setup for high throughput intact MS uses Protein Metric’s parsimonious charge deconvolution algorithm.

33:32
Characterizing the glycan shield of the Hepatitis C E1E2 glycoprotein complex using mass spectrometry

Maddy Newby takes us through the steps for unravelling the structural details of the E1E2 glycoprotein complex whilst also uncovering a novel glycan site within a non-canonical N-linked glycan site.

19:15
EU UGM 2023: Byosphere assisted biopharmaceutical development

Moving to a centralized architecture for streamlining data management, integrity and traceability. Lessons learned from a Byosphere installation.

20:31
EU UGM 2023: Friends with benefits: Glycoproteomics meets Chemical Biology

A glycoproteomics platform comprising custom chemical probes and time resolved proteolysis of biogicals.

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