Request demo
Featured Resources
41.26
Unraveling the Twin Tales of Biosimilar and Innovator Glycans

N-glycans are omnipresent in the Fc region of monoclonal antibody products. Modifications to a glycan profile can impact a protein’s stability/folding, binding affinities, effector functions, clearance rates, and/or immunogenicity.
7:03
Unravelling the glycosylation of the SARS-CoV-2 spike protein

The abundance of N-linked glycans across the SARS-CoV-2 spike protein is a potential source of heterogeneity between the many different vaccine candidates under investigation.

7:01
Automated Data Filtering for Rapid Sample Comparison of Human Milk Glycoproteins

당단백질 분류에 대한 흥미로운 연구 자료를 Protein Metrics Resources 페이지에서 보실 수 있습니다

44:35
In-Depth Sequence Variant Analysis

SVs, considered impurities, exist at low levels and are challenging to detect and characterize. Learn about automated and flexible identification of these low abundance species
4:20
Chemical probing provides insight into the native assembly state of a bacterial microcompartment

Bacterial microcompartments (BMCs) are widespread in bacteria and are used for a variety of metabolic purposes -authors used cross-linking probes to unravel the native assembly states of these large complexes.

5:04
Streamlining the Characterization of Disulfide Bond Shuffling and Protein Degradation in IgG1 Biopharmaceuticals Under Native and Stressed Conditions

By performing a semi-automated mass spectrometry method for characterizing disulfide bonds, as well as the SEC and SDS-PAGE methods, the authors were able to more seamlessly identify how bevacizumab and rituximab differ in their disulfide bond profile and degradation propensity.

7:53
Proteomic Analysis of Adenovirus 5 by UHPLC-MS/MS: Development of a Robust and Reproducible Sample Preparation Workflow

The novel workflow for AdV VP analysis affords substantially lower analysis times than traditional peptide mapping methods, which require the use of several proteases and long sample processing for sufficient in-depth characterization.

6:25
Optimization of a Label-Free Peptide Quantitation Strategy for Analysis of Therapeutic Proteins

Roche’s work underscores the importance of selecting an accurate strategy for PTM analysis, and shows the application of a customized report template and dynamic columns feature to optimize label-free peptide quantitation strategies
posters
published articles
Briefs
Insights
Download Information & system requirements
×