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Featured Resources
1:01:35
Real Time Monitoring of Bioprocess & Beyond – A Process Analytical Perspective

Presented by Bristol Meyers Squibb and Protein Metrics. A roadmap for successful implementation of PAT tools - identification of critical quality attributes and critical control points of the bioprocess for efficient and smarter development.

3:03
Orthogonal Comparison of Analytical Methods by Intact Reconstruction

By using bottom-up data to build a theoretical reconstruction of the intact data and then juxtaposing it with the experimental intact data, differences and similarities between the two orthogonal methods can quickly be qualitatively determined.

29:34
Biosimilar Characterization

Seamlessly move between non-GxP and GxP to satisfy regulatory requirements with Byosphere. Regardless of the mass spec platform scientists can create workflows that allow comparisons with speed and with confidence
20:15
Automated Feedback Control of Protein Characteristics in a Perfusion Bioprocess

“Open-loop control” is standard control strategy for biomanufacturing – Critical Quality Attributes (CQAs) are maintained within set ranges by controlling Critical Process Parameters (CPPs). Mass spectrometry is an ideal tool for PAT.

48:47
Stanford SUMS Seminar - Connecting LC-MS data analysis with non-MS techniques

In this talk, Dr Carlson reviews recent updates to the Protein Metrics platform and talk about the “next steps” of informing MS-level experiments with information from biology and process, as well as what all mass spectrometrists already proclaim, that we can inform biology in reverse.

33:49
Monitoring System Suitability – Byosphere Dashboards

Comparing batches? Assessing digestion completion? Tracking over-alkylation? Learn about the rational for the types of dashboard constructed to monitor these important aspects of laboratory operations.
33:28
質量分析によるオリゴヌクレオチド分析：配列の表示および自動化はもはやシーシュポスの作業（果てしない徒労）ではない

For fast ranking during expression vector design and clone selection, Lonza's setup for high throughput intact MS uses Protein Metric’s parsimonious charge deconvolution algorithm.
26:24
EU UGM 2023: The Growing Importance and Changing Needs for Data Analysis & Informatics – US UGM

The latest on our Oligo workflows including long digested oligonucleotides - especially mRNAs
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